Umbilical mesenchymal stem cell-derived exosomes facilitate spinal cord functional recovery through the miR-199a-3p/145-5p-mediated NGF/TrkA signaling pathway in rats

BACKGROUND: Although exosomes, as byproducts of human umbilical cord mesenchymal stem cells (hUC-MSCs), have been demonstrated to be an effective therapy for traumatic spinal cord injury (SCI), their mechanism of action remains unclear. METHODS: We designed and performed this study to determine whet...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Lai, Xunwei, Wu, Depeng, Liu, Bin, Wang, Nanxiang, Rong, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879635/
https://www.ncbi.nlm.nih.gov/pubmed/33579361
http://dx.doi.org/10.1186/s13287-021-02148-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879635/
https://www.ncbi.nlm.nih.gov/pubmed/33579361
http://dx.doi.org/10.1186/s13287-021-02148-5

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