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Feasibility of a modified search, coagulation, and clipping method with and without the use of polyglycolic acid sheets and fibrin glue for preventing delayed bleeding after gastric endoscopic submucosal dissection

BACKGROUND: Methods have been developed for preventing delayed bleeding (DB) after gastric endoscopic submucosal dissection (GESD). However, none of the methods can completely prevent DB. We hypothesized that DB could be prevented by a modified search, coagulation, and clipping (MSCC) method for pat...

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Autores principales: Abiko, Satoshi, Oda, Soichiro, Meno, Akimitsu, Shido, Akane, Yoshida, Sonoe, Yoshikawa, Ayumu, Harada, Kazuaki, Kawagishi, Naoki, Sano, Itsuki, Oda, Hisashi, Miyagishima, Takuto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879694/
https://www.ncbi.nlm.nih.gov/pubmed/33573607
http://dx.doi.org/10.1186/s12876-020-01539-x
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author Abiko, Satoshi
Oda, Soichiro
Meno, Akimitsu
Shido, Akane
Yoshida, Sonoe
Yoshikawa, Ayumu
Harada, Kazuaki
Kawagishi, Naoki
Sano, Itsuki
Oda, Hisashi
Miyagishima, Takuto
author_facet Abiko, Satoshi
Oda, Soichiro
Meno, Akimitsu
Shido, Akane
Yoshida, Sonoe
Yoshikawa, Ayumu
Harada, Kazuaki
Kawagishi, Naoki
Sano, Itsuki
Oda, Hisashi
Miyagishima, Takuto
author_sort Abiko, Satoshi
collection PubMed
description BACKGROUND: Methods have been developed for preventing delayed bleeding (DB) after gastric endoscopic submucosal dissection (GESD). However, none of the methods can completely prevent DB. We hypothesized that DB could be prevented by a modified search, coagulation, and clipping (MSCC) method for patients at low risk for DB and by combining the use of polyglycolic acid sheets and fibrin glue with the MSCC method (PMSCC method) for patients at high risk for DB (antibleeding [ABI] strategy). This study assessed the technical feasibility of this novel strategy. METHOD: We investigated 123 lesions in 121 consecutive patients who underwent GESD in Kushiro Rosai Hospital between April 2018 and January 2020. The decision for continuation or cessation of antithrombotic agents was based on the Guidelines for Gastroenterological Endoscopy in Patients Undergoing Antithrombotic Treatment. RESULTS: Oral antithrombotic agents were administered to 28 patients (22.8%). The en bloc R0 resection rate was 98.4%. The MSCC method and the PMSCC method for preventing DB were performed in 114 and 9 lesions, respectively. The median time of the MSCC method was 16 min, and the median speed (the resection area divided by the time of method used) was 3.6 cm(2)/10 min. The median time of the PMSCC method was 59 min, and the median speed was 1.3 cm(2)/10 min. The only delayed procedural adverse event was DB in 1 (0.8%) of the 123 lesions. CONCLUSIONS: The ABI strategy is feasible for preventing DB both in patients at low risk and in those at high risk for DB after GESD, whereas the PMSCC method may be necessary for reduction of time.
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spelling pubmed-78796942021-02-17 Feasibility of a modified search, coagulation, and clipping method with and without the use of polyglycolic acid sheets and fibrin glue for preventing delayed bleeding after gastric endoscopic submucosal dissection Abiko, Satoshi Oda, Soichiro Meno, Akimitsu Shido, Akane Yoshida, Sonoe Yoshikawa, Ayumu Harada, Kazuaki Kawagishi, Naoki Sano, Itsuki Oda, Hisashi Miyagishima, Takuto BMC Gastroenterol Research Article BACKGROUND: Methods have been developed for preventing delayed bleeding (DB) after gastric endoscopic submucosal dissection (GESD). However, none of the methods can completely prevent DB. We hypothesized that DB could be prevented by a modified search, coagulation, and clipping (MSCC) method for patients at low risk for DB and by combining the use of polyglycolic acid sheets and fibrin glue with the MSCC method (PMSCC method) for patients at high risk for DB (antibleeding [ABI] strategy). This study assessed the technical feasibility of this novel strategy. METHOD: We investigated 123 lesions in 121 consecutive patients who underwent GESD in Kushiro Rosai Hospital between April 2018 and January 2020. The decision for continuation or cessation of antithrombotic agents was based on the Guidelines for Gastroenterological Endoscopy in Patients Undergoing Antithrombotic Treatment. RESULTS: Oral antithrombotic agents were administered to 28 patients (22.8%). The en bloc R0 resection rate was 98.4%. The MSCC method and the PMSCC method for preventing DB were performed in 114 and 9 lesions, respectively. The median time of the MSCC method was 16 min, and the median speed (the resection area divided by the time of method used) was 3.6 cm(2)/10 min. The median time of the PMSCC method was 59 min, and the median speed was 1.3 cm(2)/10 min. The only delayed procedural adverse event was DB in 1 (0.8%) of the 123 lesions. CONCLUSIONS: The ABI strategy is feasible for preventing DB both in patients at low risk and in those at high risk for DB after GESD, whereas the PMSCC method may be necessary for reduction of time. BioMed Central 2021-02-11 /pmc/articles/PMC7879694/ /pubmed/33573607 http://dx.doi.org/10.1186/s12876-020-01539-x Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Abiko, Satoshi
Oda, Soichiro
Meno, Akimitsu
Shido, Akane
Yoshida, Sonoe
Yoshikawa, Ayumu
Harada, Kazuaki
Kawagishi, Naoki
Sano, Itsuki
Oda, Hisashi
Miyagishima, Takuto
Feasibility of a modified search, coagulation, and clipping method with and without the use of polyglycolic acid sheets and fibrin glue for preventing delayed bleeding after gastric endoscopic submucosal dissection
title Feasibility of a modified search, coagulation, and clipping method with and without the use of polyglycolic acid sheets and fibrin glue for preventing delayed bleeding after gastric endoscopic submucosal dissection
title_full Feasibility of a modified search, coagulation, and clipping method with and without the use of polyglycolic acid sheets and fibrin glue for preventing delayed bleeding after gastric endoscopic submucosal dissection
title_fullStr Feasibility of a modified search, coagulation, and clipping method with and without the use of polyglycolic acid sheets and fibrin glue for preventing delayed bleeding after gastric endoscopic submucosal dissection
title_full_unstemmed Feasibility of a modified search, coagulation, and clipping method with and without the use of polyglycolic acid sheets and fibrin glue for preventing delayed bleeding after gastric endoscopic submucosal dissection
title_short Feasibility of a modified search, coagulation, and clipping method with and without the use of polyglycolic acid sheets and fibrin glue for preventing delayed bleeding after gastric endoscopic submucosal dissection
title_sort feasibility of a modified search, coagulation, and clipping method with and without the use of polyglycolic acid sheets and fibrin glue for preventing delayed bleeding after gastric endoscopic submucosal dissection
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879694/
https://www.ncbi.nlm.nih.gov/pubmed/33573607
http://dx.doi.org/10.1186/s12876-020-01539-x
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