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Dextromethorphan improved cyclosporine-induced depression in mice model of despair

BACKGROUND AND PURPOSE: Cyclosporine (Cyc) is a calcineurin inhibitor used in immunosuppressive therapy that may cause psychological problems such as depression. Previous investigations have shown the positive antidepressant effects of dextromethorphan (Dxt). Therefore, the aim of this study was the...

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Detalles Bibliográficos
Autores principales: Mesripour, Azadeh, Golbidi, Mojgan, Hajhashemi, Valiollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879785/
https://www.ncbi.nlm.nih.gov/pubmed/33628286
http://dx.doi.org/10.4103/1735-5362.297847

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