Revealing Tissue-Specific SARS-CoV-2 Infection and Host Responses using Human Stem Cell-Derived Lung and Cerebral Organoids

COVID-19 is a transmissible respiratory disease caused by a novel coronavirus, SARS-CoV-2, and has become a global health emergency. There is an urgent need for robust and practical in vitro model systems to investigate viral pathogenesis. Here, we generated human induced pluripotent stem cell (iPSC...

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Detalles Bibliográficos
Autores principales: Tiwari, Shashi Kant, Wang, Shaobo, Smith, Davey, Carlin, Aaron F., Rana, Tariq M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879814/
https://www.ncbi.nlm.nih.gov/pubmed/33631122
http://dx.doi.org/10.1016/j.stemcr.2021.02.005

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