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Changes in the parameters of the rectoanal inhibitory reflex in children with functional constipation and large rectum

BACKGROUND: Abdominal ultrasound and anorectal manometry are part of the investigations used to assess children with functional constipation. This study aimed at assessing the changes in the characteristics of the rectoanal inhibitory reflex (RAIR) in children with functional constipation and correl...

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Autores principales: Pop, Daniela, Tătar, Simona, Fufezan, Otilia, Farcău, Dorin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iuliu Hatieganu University of Medicine and Pharmacy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880069/
https://www.ncbi.nlm.nih.gov/pubmed/33629052
http://dx.doi.org/10.15386/mpr-1894
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author Pop, Daniela
Tătar, Simona
Fufezan, Otilia
Farcău, Dorin
author_facet Pop, Daniela
Tătar, Simona
Fufezan, Otilia
Farcău, Dorin
author_sort Pop, Daniela
collection PubMed
description BACKGROUND: Abdominal ultrasound and anorectal manometry are part of the investigations used to assess children with functional constipation. This study aimed at assessing the changes in the characteristics of the rectoanal inhibitory reflex (RAIR) in children with functional constipation and correlating them with the dimensions of the rectum, measured by abdominal ultrasound. A secondary objective was to compare the rectum size in children with and without constipation. METHOD: We retrospectively reviewed the clinical data and investigations results of 51 children (mean age±standard deviation (SD) = 5.8±3.5 years) with functional constipation who came to our clinic between January 2013 and February 2020. The assessment of these patients included both the assessment of the transverse diameter of the rectal ampulla by abdominal ultrasound and anorectal manometry. The studied parameters of RAIR were: the minimal volume of air necessary to induce RAIR, in all the patients with functional constipation, and in 20 of them, relaxation time, latency and relaxation percentage. A control group was formed of 27 children (mean age±SD = 5.1±4 years) without digestive diseases and with normal intestinal transit, who were assessed by abdominal ultrasound. RESULTS: The mean value ±SD of the volume of air necessary to induce RAIR was 21.9±12.1 cm3 air. There was no correlation between the rectum transverse diameter and the minimal air volume that triggered RAIR (r=−0.01, p=0.94). The mean value ±SD of the transverse diameter of the rectum in patients with functional constipation was 39±14 mm, and in children without constipation 26±6 mm (p<0.05). The mean duration of the symptoms in children with functional constipation was 2.8 years. CONCLUSIONS: There were no correlations between the volume of air that induced the RAIR and the transverse diameter of the rectum in children with functional constipation. The transverse diameter of the rectum was increased in children with long-term functional constipation.
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spelling pubmed-78800692021-02-23 Changes in the parameters of the rectoanal inhibitory reflex in children with functional constipation and large rectum Pop, Daniela Tătar, Simona Fufezan, Otilia Farcău, Dorin Med Pharm Rep Original Research BACKGROUND: Abdominal ultrasound and anorectal manometry are part of the investigations used to assess children with functional constipation. This study aimed at assessing the changes in the characteristics of the rectoanal inhibitory reflex (RAIR) in children with functional constipation and correlating them with the dimensions of the rectum, measured by abdominal ultrasound. A secondary objective was to compare the rectum size in children with and without constipation. METHOD: We retrospectively reviewed the clinical data and investigations results of 51 children (mean age±standard deviation (SD) = 5.8±3.5 years) with functional constipation who came to our clinic between January 2013 and February 2020. The assessment of these patients included both the assessment of the transverse diameter of the rectal ampulla by abdominal ultrasound and anorectal manometry. The studied parameters of RAIR were: the minimal volume of air necessary to induce RAIR, in all the patients with functional constipation, and in 20 of them, relaxation time, latency and relaxation percentage. A control group was formed of 27 children (mean age±SD = 5.1±4 years) without digestive diseases and with normal intestinal transit, who were assessed by abdominal ultrasound. RESULTS: The mean value ±SD of the volume of air necessary to induce RAIR was 21.9±12.1 cm3 air. There was no correlation between the rectum transverse diameter and the minimal air volume that triggered RAIR (r=−0.01, p=0.94). The mean value ±SD of the transverse diameter of the rectum in patients with functional constipation was 39±14 mm, and in children without constipation 26±6 mm (p<0.05). The mean duration of the symptoms in children with functional constipation was 2.8 years. CONCLUSIONS: There were no correlations between the volume of air that induced the RAIR and the transverse diameter of the rectum in children with functional constipation. The transverse diameter of the rectum was increased in children with long-term functional constipation. Iuliu Hatieganu University of Medicine and Pharmacy 2021-01 2021-01-29 /pmc/articles/PMC7880069/ /pubmed/33629052 http://dx.doi.org/10.15386/mpr-1894 Text en This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (http://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Original Research
Pop, Daniela
Tătar, Simona
Fufezan, Otilia
Farcău, Dorin
Changes in the parameters of the rectoanal inhibitory reflex in children with functional constipation and large rectum
title Changes in the parameters of the rectoanal inhibitory reflex in children with functional constipation and large rectum
title_full Changes in the parameters of the rectoanal inhibitory reflex in children with functional constipation and large rectum
title_fullStr Changes in the parameters of the rectoanal inhibitory reflex in children with functional constipation and large rectum
title_full_unstemmed Changes in the parameters of the rectoanal inhibitory reflex in children with functional constipation and large rectum
title_short Changes in the parameters of the rectoanal inhibitory reflex in children with functional constipation and large rectum
title_sort changes in the parameters of the rectoanal inhibitory reflex in children with functional constipation and large rectum
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880069/
https://www.ncbi.nlm.nih.gov/pubmed/33629052
http://dx.doi.org/10.15386/mpr-1894
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