Adjunctive IgM-enriched immunoglobulin therapy with a personalised dose based on serum IgM-titres versus standard dose in the treatment of septic shock: a randomised controlled trial (IgM-fat trial)

INTRODUCTION: In patients with septic shock, low levels of circulating immunoglobulins are common and their kinetics appear to be related to clinical outcome. The pivotal role of immunoglobulins in the host immune response to infection suggests that additional therapy with polyclonal intravenous imm...

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Detalles Bibliográficos
Autores principales: Biagioni, Emanuela, Tosi, Martina, Berlot, Giorgio, Castiglione, Giacomo, Corona, Alberto, De Cristofaro, Maria Giovanna, Donati, Abele, Feltracco, Paolo, Forfori, Francesco, Fragranza, Fiorentino, Murino, Patrizia, Piazza, Ornella, Tullo, Livio, Grasselli, Giacomo, D'Amico, Roberto, Girardis, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Intensive Care
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880103/
https://www.ncbi.nlm.nih.gov/pubmed/33574139
http://dx.doi.org/10.1136/bmjopen-2019-036616

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