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Explaining Divergent Observations Regarding Osteocalcin/GPRC6A Endocrine Signaling
A new schema proposes that the bone-derived osteocalcin (Ocn) peptide hormone activates the G-protein–coupled receptor GPRC6A to directly regulate glucose and fat metabolism in liver, muscle, and fat, and to stimulate the release of metabolism-regulating hormones, including insulin, fibroblast growt...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880225/ https://www.ncbi.nlm.nih.gov/pubmed/33474566 http://dx.doi.org/10.1210/endocr/bqab011 |