Chondroitinase and Antidepressants Promote Plasticity by Releasing TRKB from Dephosphorylating Control of PTPσ in Parvalbumin Neurons

Perineuronal nets (PNNs) are an extracellular matrix structure rich in chondroitin sulfate proteoglycans (CSPGs), which preferentially encase parvalbumin-containing (PV(+)) interneurons. PNNs restrict cortical network plasticity but the molecular mechanisms involved are unclear. We found that reacti...

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Detalles Bibliográficos
Autores principales: Lesnikova, Angelina, Casarotto, Plinio Cabrera, Fred, Senem Merve, Voipio, Mikko, Winkel, Frederike, Steinzeig, Anna, Antila, Hanna, Umemori, Juzoh, Biojone, Caroline, Castrén, Eero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880295/
https://www.ncbi.nlm.nih.gov/pubmed/33293360
http://dx.doi.org/10.1523/JNEUROSCI.2228-20.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880295/
https://www.ncbi.nlm.nih.gov/pubmed/33293360
http://dx.doi.org/10.1523/JNEUROSCI.2228-20.2020

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