Cargando…

Transplanting Rac1-silenced bone marrow mesenchymal stem cells promote neurological function recovery in TBI mice

Bone marrow mesenchymal stem cells (BMMSCs)-based therapy has emerged as a promising novel therapy for Traumatic Brain Injury (TBI). However, the therapeutic quantity of viable implanted BMMSCs necessary to initiate efficacy is still undetermined. Increased oxidative stress following TBI, which lead...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Dongdong, Siaw-Debrah, Felix, Wang, Hua, Ye, Sheng, Wang, Kankai, Wu, Ke, Zhang, Ying, Wang, Hao, Yao, Chaojie, Chen, Jiayu, Yan, Lin, Zhang, Chun-Li, Zhuge, Qichuan, Yang, Jianjing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880331/ https://www.ncbi.nlm.nih.gov/pubmed/33411679 http://dx.doi.org/10.18632/aging.202334

Ejemplares similares

NT3(P75-2) gene-modified bone mesenchymal stem cells improve neurological function recovery in mouse TBI model
por: Wu, Ke, et al.
Publicado: (2019)

Transplantation of Roxadustat‐preconditioned bone marrow stromal cells improves neurological function recovery through enhancing grafted cell survival in ischemic stroke rats
por: Chen, Jiayu, et al.
Publicado: (2022)

Pyridoxal Isonicotinoyl Hydrazone Improves Neurological Recovery by Attenuating Ferroptosis and Inflammation in Cerebral Hemorrhagic Mice
por: Zhang, Hengli, et al.
Publicado: (2021)

VX765 Attenuates Pyroptosis and HMGB1/TLR4/NF-κB Pathways to Improve Functional Outcomes in TBI Mice
por: Sun, Zhezhe, et al.
Publicado: (2020)

PTBP1 knockdown promotes neural differentiation of glioblastoma cells through UNC5B receptor
por: Wang, Kankai, et al.
Publicado: (2022)

Establishment of a Modified and Standardized Ferric Chloride-Induced Rat Carotid Artery Thrombosis Model
por: Lin, Xiao, et al.
Publicado: (2022)

Improving on Laboratory Traumatic Brain Injury Models to Achieve Better Results
por: Nyanzu, Mark, et al.
Publicado: (2017)

Exosomes Derived From Bone Mesenchymal Stem Cells Ameliorate Early Inflammatory Responses Following Traumatic Brain Injury
por: Ni, Haoqi, et al.
Publicado: (2019)

Interleukin-4 Ameliorates the Functional Recovery of Intracerebral Hemorrhage Through the Alternative Activation of Microglia/Macrophage
por: Yang, Jianjing, et al.
Publicado: (2016)

Preclinical Studies and Translational Applications of Intracerebral Hemorrhage
por: Siaw-Debrah, Felix, et al.
Publicado: (2017)

ANXA1 as a Prognostic and Immune Microenvironmental Marker for Gliomas Based on Transcriptomic Analysis and Experimental Validation
por: Lin, Zhongxiao, et al.
Publicado: (2021)

Shikonin regulates autophagy via the AMPK/mTOR pathway and reduces apoptosis of human umbilical cord mesenchymal stem cells to improve survival in tissues surrounding brain contusion
por: Zhu, Xiaohong, et al.
Publicado: (2021)

Melatonin Enhances the Therapeutic Effect of Plasma Exosomes Against Cerebral Ischemia-Induced Pyroptosis Through the TLR4/NF-κB Pathway
por: Wang, Kankai, et al.
Publicado: (2020)

AC-YVAD-CMK Inhibits Pyroptosis and Improves Functional Outcome after Intracerebral Hemorrhage
por: Lin, Xiao, et al.
Publicado: (2018)

Calpain inhibitor MDL28170 improves the transplantation-mediated therapeutic effect of bone marrow-derived mesenchymal stem cells following traumatic brain injury
por: Hu, Jiangnan, et al.
Publicado: (2019)

A Reliable Nonhuman Primate Model of Ischemic Stroke with Reproducible Infarct Size and Long-term Sensorimotor Deficits
por: Lin, Xiao, et al.
Publicado: (2023)

Baicalin reverses the impairment of synaptogenesis induced by dopamine burden via the stimulation of GABA(A)R–TrkB interaction in minimal hepatic encephalopathy
por: Ding, Saidan, et al.
Publicado: (2018)

DA Negatively Regulates IGF-I Actions Implicated in Cognitive Function via Interaction of PSD95 and nNOS in Minimal Hepatic Encephalopathy
por: Ding, Saidan, et al.
Publicado: (2017)

VX‐765 enhances autophagy of human umbilical cord mesenchymal stem cells against stroke‐induced apoptosis and inflammatory responses via AMPK/mTOR signaling pathway
por: Sun, Zhezhe, et al.
Publicado: (2020)

Ablation of GSDMD Improves Outcome of Ischemic Stroke Through Blocking Canonical and Non-canonical Inflammasomes Dependent Pyroptosis in Microglia
por: Wang, Kankai, et al.
Publicado: (2020)

Prospects of Directly Reprogrammed Adult Human Neurons for Neurodegenerative Disease Modeling and Drug Discovery: iN vs. iPSCs Models
por: Zhang, Ying, et al.
Publicado: (2020)

Dopamine Burden Induced the Inactivation of Sonic Hedgehog Signaling to Cognitive Decline in Minimal Hepatic Encephalopathy
por: Ding, Saidan, et al.
Publicado: (2017)

GBE1 Promotes Glioma Progression by Enhancing Aerobic Glycolysis through Inhibition of FBP1
por: Chen, Zhen, et al.
Publicado: (2023)

Conventional craniotomy versus conservative treatment in patients with minor spontaneous intracerebral hemorrhage in the basal ganglia
por: Wang, Ning, et al.
Publicado: (2022)

Aging induced decline in T-lymphopoiesis is primarily dependent on status of progenitor niches in the bone marrow and thymus
por: Sun, Liguang, et al.
Publicado: (2012)

Elevated blood urea nitrogen is associated with recurrence of post-operative chronic subdural hematoma
por: Wang, Ning, et al.
Publicado: (2020)

Nutritional interventions to support acute mTBI recovery
por: Finnegan, Emma, et al.
Publicado: (2022)

Inhibition of mammalian target of rapamycin improves neurobehavioral deficit and modulates immune response after intracerebral hemorrhage in rat
por: Lu, Qin, et al.
Publicado: (2014)

mTBI-Induced Systemic Vascular Dysfunction in a Mouse mTBI Model
por: Lv, Weizhen, et al.
Publicado: (2022)

NeuroD4 converts glioblastoma cells into neuron-like cells through the SLC7A11-GSH-GPX4 antioxidant axis
por: Wang, Hao, et al.
Publicado: (2023)

By up-regulating μ- and δ-opioid receptors, neuron-restrictive silencer factor knockdown promotes neurological recovery after ischemia
por: Liang, Hui-Min, et al.
Publicado: (2017)

Silencing of Rac1 expression via RNA interference inhibits retinal neovascularization in rats
por: Li, Juanjuan, et al.
Publicado: (2012)

How Can Providers Better Address Recovery Needs for Geriatric TBI Survivors?
por: Vogel, Mia, et al.
Publicado: (2021)

A case–control study examining whether neurological deficits and PTSD in combat veterans are related to episodes of mild TBI
por: Ruff, Robert Louis, et al.
Publicado: (2012)

COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI)
por: Smith, Douglas H., et al.
Publicado: (2021)

Dosimetric Evaluation Between the Conventional Volumetrically Modulated Arc Therapy (VMAT) Total Body Irradiation (TBI) and the Novel Simultaneous Integrated Total Marrow Approach (SIMBa) VMAT TBI
por: Stanley, Dennis, et al.
Publicado: (2021)

Microglial polarization in TBI: Signaling pathways and influencing pharmaceuticals
por: Li, Yun-Fei, et al.
Publicado: (2022)

Predicting the post-treatment recovery of patients suffering from traumatic brain injury (TBI)
por: Siddiqui, Zaigham Faraz, et al.
Publicado: (2015)

OTHER-06 EPIDEMIOLOGY OF BRAIN AND SPINE TUMOURS – A SINGLE CENTRE DESCRIPTIVE RETROSPECTIVE STUDY
por: Banson, Mabel, et al.
Publicado: (2023)

S-Adenosylmethionine suppresses the expression of Smad3/4 in activated human hepatic stellate cells via Rac1 promoter methylation
por: BIAN, KANGQI, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_cllet253t60b9rs3toaiqqc89t