Effective natural inhibitors targeting poly ADP-ribose polymerase by computational study

Object: This study was designed to screen ideal lead compounds and drug candidates with an inhibitory effect on PARP from the drug library (ZINC database). Results: Two effective natural compounds ZINC000003938684 and ZINC000014811844 were found to bind to PARP in the ZINC database, showing a higher...

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Detalles Bibliográficos
Autores principales: Zhong, Sheng, Wu, Bo, Yang, Wenzhuo, Ge, Junliang, Zhang, Xiangheng, Chen, Zhenghe, Duan, Hao, He, Zhenqiang, Liu, Yibing, Wang, Hongyu, Jiang, Yuting, Zhang, Zhiyun, Wang, Xinhui, Li, Weihang, Liu, Naimeng, Guo, Xiaoyu, Mou, Yonggao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880371/
https://www.ncbi.nlm.nih.gov/pubmed/33486472
http://dx.doi.org/10.18632/aging.103986

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