Den molekularen Wirtszellveränderungen durch SARS-CoV-2 auf der Spur

Upon infection with SARS-CoV-2, a variety of changes happen inside the host cell. The virus hijacks host cell pathways for driving its own replication, while the host counteracts with response mechanisms. To gain a comprehensive understanding of COVID-19, caused by SARS-CoV-2 infection, and develop...

Descripción completa

Detalles Bibliográficos
Autores principales: Klann, Kevin, Münch, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Wissenschaft
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880639/
https://www.ncbi.nlm.nih.gov/pubmed/33612988
http://dx.doi.org/10.1007/s12268-021-1535-3
Descripción
Sumario:Upon infection with SARS-CoV-2, a variety of changes happen inside the host cell. The virus hijacks host cell pathways for driving its own replication, while the host counteracts with response mechanisms. To gain a comprehensive understanding of COVID-19, caused by SARS-CoV-2 infection, and develop therapeutic strategies, it is crucial to observe these systematic changes in their entirety. In our recent studies, we followed the effects of SARS-CoV-2 infection on the human proteome, which led to the identification of several drugs that abolished viral proliferation in cells.

Ejemplares similares