Curcumin promotes AApoAII amyloidosis and peroxisome proliferation in mice by activating the PPARα signaling pathway

Curcumin is a polyphenol compound that exhibits multiple physiological activities. To elucidate the mechanisms by which curcumin affects systemic amyloidosis, we investigated amyloid deposition and molecular changes in a mouse model of amyloid apolipoprotein A-II (AApoAII) amyloidosis, in which mice...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Jian, Li, Ying, Kametani, Fuyuki, Cui, Xiaoran, Igarashi, Yuichi, Huo, Jia, Miyahara, Hiroki, Mori, Masayuki, Higuchi, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880682/
https://www.ncbi.nlm.nih.gov/pubmed/33496266
http://dx.doi.org/10.7554/eLife.63538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880682/
https://www.ncbi.nlm.nih.gov/pubmed/33496266
http://dx.doi.org/10.7554/eLife.63538

Ejemplares similares