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Curcumin promotes AApoAII amyloidosis and peroxisome proliferation in mice by activating the PPARα signaling pathway

Curcumin is a polyphenol compound that exhibits multiple physiological activities. To elucidate the mechanisms by which curcumin affects systemic amyloidosis, we investigated amyloid deposition and molecular changes in a mouse model of amyloid apolipoprotein A-II (AApoAII) amyloidosis, in which mice...

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Detalles Bibliográficos
Autores principales:	Dai, Jian, Li, Ying, Kametani, Fuyuki, Cui, Xiaoran, Igarashi, Yuichi, Huo, Jia, Miyahara, Hiroki, Mori, Masayuki, Higuchi, Keiichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880682/ https://www.ncbi.nlm.nih.gov/pubmed/33496266 http://dx.doi.org/10.7554/eLife.63538

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