Pten-NOLC1 Fusion Promotes Cancers Involving MET and EGFR Signalings

Inactivation of Pten gene through deletions and mutations leading to excessive pro-growth signaling pathway activations frequently occurs in cancers. Here, we report a Pten derived pro-cancer growth gene fusion Pten-NOLC1 originated from a chr10 genome rearrangement and identified through a transcri...

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Detalles Bibliográficos
Autores principales: Luo, Jian-Hua, Liu, Silvia, Tao, Junyan, Ren, Bao-Guo, Luo, Katherine, Chen, Zhang-Hui, Nalesnik, Michael, Cieply, Kathleen, Ma, Tianzhou, Cheng, Shi-Yuan, Chen, Qi, Michalopoulos, George K., Nelson, Joel B., Bhargava, Rohit, Zhang, Jun, Ma, Deqin, Jarrard, David, Pennathur, Arjun, Luketich, James D., DeFranco, Donald B., Monga, Satdarshan Paul, Tseng, George, Yu, Yan-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7880894/
https://www.ncbi.nlm.nih.gov/pubmed/33323972
http://dx.doi.org/10.1038/s41388-020-01582-8

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