Acute glucose influx-induced mitochondrial hyperpolarization inactivates myosin phosphatase as a novel mechanism of vascular smooth muscle contraction

It is well-established that long-term exposure of the vasculature to metabolic disturbances leads to abnormal vascular tone, while the physiological regulation of vascular tone upon acute metabolic challenge remains unknown. Here, we found that acute glucose challenge induced transient increases in...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Yang, Hongyan, Yang, Lu, Wang, Zhen, Qin, Xinghua, Zhou, Jiaheng, Dong, Ling, Li, Jia, Zhu, Minsheng, Zhang, Xing, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881016/
https://www.ncbi.nlm.nih.gov/pubmed/33579894
http://dx.doi.org/10.1038/s41419-021-03462-9

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