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pH-dependent and dynamic interactions of cystatin C with heparan sulfate

Cystatin C (Cst-3) is a potent inhibitor of cysteine proteases with diverse biological functions. As a secreted protein, the potential interaction between Cst-3 and extracellular matrix components has not been well studied. Here we investigated the interaction between Cst-3 and heparan sulfate (HS),...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoxiao, Liu, Xinyue, Su, Guowei, Li, Miaomiao, Liu, Jian, Wang, Chunyu, Xu, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881039/
https://www.ncbi.nlm.nih.gov/pubmed/33580179
http://dx.doi.org/10.1038/s42003-021-01737-7