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Chromatin accessibility of circulating CD8(+) T cells predicts treatment response to PD-1 blockade in patients with gastric cancer

Although tumor genomic profiling has identified small subsets of gastric cancer (GC) patients with clinical benefit from anti-PD-1 treatment, not all responses can be explained by tumor sequencing alone. We investigate epigenetic elements responsible for the differential response to anti-PD-1 therap...

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Detalles Bibliográficos
Autores principales:	Shin, Hyun Mu, Kim, Gwanghun, Kim, Sangjib, Sim, Ji Hyun, Choi, Jiyeob, Kim, Minji, Kwon, Minsuk, Ye, Sang-Kyu, Lee, Dong-Sup, Cho, Seung Woo, Kim, Seung Tae, Lee, Jeeyun, Kim, Hang-Rae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881150/ https://www.ncbi.nlm.nih.gov/pubmed/33579944 http://dx.doi.org/10.1038/s41467-021-21299-w

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