Cargando…

Exploring the mechanism of (-)-Epicatechin on premature ovarian insufficiency based on network pharmacology and experimental evaluation

Methods: Relevant potential targets for EC were obtained based on Traditional Chinese Medicine System Pharmacology Database (TCMSP), a bioinformatics analysis tool for molecular mechanism of Traditional Chinese Medicine (BATMAN-TCM) and STITCH databases. The Online Mendelian Inheritance in Man (OMIM...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Fei, Zhao, Qi, Gao, Huanpeng, Wang, Xiaomei, Xu, Ke, Wang, Yishu, Han, Fuguo, Liu, Qingfei, Shi, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881164/ https://www.ncbi.nlm.nih.gov/pubmed/33521822 http://dx.doi.org/10.1042/BSR20203955

Ejemplares similares

Network pharmacology and experimental validation to explore the molecular mechanisms of Bushen Huoxue for the treatment of premature ovarian insufficiency
por: Cao, Ying, et al.
Publicado: (2021)

Exploring the mechanism of Cassiae semen in regulating lipid metabolism through network pharmacology and experimental validation
por: Huang, Lili, et al.
Publicado: (2023)

Exploring the mechanism of Shengmai Yin for coronary heart disease based on systematic pharmacology and chemoinformatics
por: Jiang, Yan, et al.
Publicado: (2020)

Explore prognostic biomarker of bladder cancer based on competing endogenous network
por: Li, Faping, et al.
Publicado: (2020)

Study on the mechanism of Danshen-Guizhi drug pair in the treatment of ovarian cancer based on network pharmacology and in vitro experiment
por: Qin, Chongzhen, et al.
Publicado: (2022)

Utilizing network pharmacology and experimental validation to investigate the underlying mechanism of phellodendrine on inflammation
por: Hu, Lili, et al.
Publicado: (2022)

A network pharmacology approach to explore active compounds and pharmacological mechanisms of epimedium for treatment of premature ovarian insufficiency
por: Zhao, Huishan, et al.
Publicado: (2019)

Utilizing network pharmacology and molecular docking to explore the underlying mechanism of Guizhi Fuling Wan in treating endometriosis
por: Wang, Haoxian, et al.
Publicado: (2021)

Identification of quality markers for Cyanotis arachnoidea and analysis of its physiological mechanism based on chemical pattern recognition, network pharmacology, and experimental validation
por: Hu, Jingnan, et al.
Publicado: (2023)

Exploring the mechanism of cordycepin combined with doxorubicin in treating glioblastoma based on network pharmacology and biological verification
por: Chen, Jing, et al.
Publicado: (2022)

Exploring the mechanism of Danggui Buxue Decoction in regulating atherosclerotic disease network based on integrated pharmacological methods
por: Xu, Hao, et al.
Publicado: (2021)

Regulatory mechanism of Scutellaria baicalensis Georgi on bone cancer pain based on network pharmacology and experimental verification
por: Wang, Aitao, et al.
Publicado: (2022)

Exploration of the molecular targets and mechanisms of suxiao xintong dropping pills for myocardial infarction by network pharmacology method
por: Chen, Daqiu, et al.
Publicado: (2021)

Exploring the mechanism of Radix Rhei Et Rhizome intervention in intracerebral hemorrhage based on systematic pharmacology and proteomics strategy
por: Zhu, Xiaofei, et al.
Publicado: (2021)

Exploring mechanisms of Chaihu-Shugan-San against liver fibrosis by integrated multi-omics and network pharmacology approach
por: Xie, Zhihao, et al.
Publicado: (2022)

Landscape of pathogenic mutations in premature ovarian insufficiency
por: Ke, Hanni, et al.
Publicado: (2023)

Evaluation of FGFR1 as a diagnostic biomarker for ovarian cancer using TCGA and GEO datasets
por: Xiao, Huiting, et al.
Publicado: (2021)

Plasma metabolomic characterization of premature ovarian insufficiency
por: Zhou, Xing-Yu, et al.
Publicado: (2023)

Analysis of the role and mechanism of EGCG in septic cardiomyopathy based on network pharmacology
por: Wu, Ji, et al.
Publicado: (2022)

FOXP4‐AS1 is a favorable prognostic-related enhancer RNA in ovarian cancer
por: Hua, Tian, et al.
Publicado: (2021)

Morphologic and Pharmacological Investigations in the Epicatechin Gastroprotective Effect
por: Rozza, A. L., et al.
Publicado: (2012)

Analysis of differences in the transcriptomic profiles of eutopic and ectopic endometriums in women with ovarian endometriosis
por: Feng, Xiao, et al.
Publicado: (2021)

Construction of a novel prognostic-predicting model correlated to ovarian cancer
por: Tang, Weichun, et al.
Publicado: (2020)

Network Pharmacology Approach for Predicting Targets of Zishen Yutai Pills on Premature Ovarian Insufficiency
por: Feng, Yihui, et al.
Publicado: (2021)

Premature ovarian insufficiency: Pathogenesis and management
por: Fenton, Anna J.
Publicado: (2015)

Network pharmacology to investigate the pharmacological mechanisms of muscone in Xingnaojing injections for the treatment of severe traumatic brain injury
por: Liu, Zhuohang, et al.
Publicado: (2021)

DNA double-strand break genetic variants in patients with premature ovarian insufficiency
por: Ding, Xuechun, et al.
Publicado: (2023)

Network pharmacology for the identification of phytochemicals in traditional Chinese medicine for COVID-19 that may regulate interleukin-6
por: Niu, Wen-hao, et al.
Publicado: (2021)

Comprehensive genomic analysis of microenvironment phenotypes in ovarian cancer
por: Wang, Jingshu, et al.
Publicado: (2020)

Identification and validation of RNA‐binding protein‐related gene signature revealed potential associations with immunosuppression and drug sensitivity in glioma
por: Chen, Zhuohui, et al.
Publicado: (2021)

The Trends and Hotspots in Premature Ovarian Insufficiency Therapy from 2000 to 2022
por: Tong, Yan, et al.
Publicado: (2022)

Identification of metastasis and prognosis-associated genes for serous ovarian cancer
por: Yang, Yijun, et al.
Publicado: (2020)

Therapeutic options for premature ovarian insufficiency: an updated review
por: Huang, Qiao-yi, et al.
Publicado: (2022)

Uncovering the relationship and mechanisms of Tartary buckwheat (Fagopyrum tataricum) and Type II diabetes, hypertension, and hyperlipidemia using a network pharmacology approach
por: Lu, Chao-Long, et al.
Publicado: (2017)

Application of network pharmacology in the study of mechanism of Chinese medicine in the treatment of ulcerative colitis: A review
por: Zheng, Shihao, et al.
Publicado: (2022)

BCAA insufficiency leads to premature ovarian insufficiency via ceramide‐induced elevation of ROS
por: Guo, Xiao, et al.
Publicado: (2023)

Integrative bioinformatics and experimental analysis revealed down-regulated CDC42EP3 as a novel prognostic target for ovarian cancer and its roles in immune infiltration
por: Yan, Yuanliang, et al.
Publicado: (2021)

Prognostic values of GMPS, PR, CD40, and p21 in ovarian cancer
por: Wang, Ping, et al.
Publicado: (2019)

ZNF76 predicts prognosis and response to platinum chemotherapy in human ovarian cancer
por: Hua, Tian, et al.
Publicado: (2021)

Uncovering the mechanism of Ge-Gen-Qin-Lian decoction for treating ulcerative colitis based on network pharmacology and molecular docking verification
por: Xu, Lin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_852cpsf15fn6otvnrhktgc14t8