Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients?

Among 275 patients with COVID-19, we found that median blood zinc level was significantly lower in patients with poor clinical outcome (N = 75) as compared to patients with good clinical outcome (N = 200) (840 μg/L versus 970 μg/L; p < 0.0001), suggesting that zinc supplementation could be useful...

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Autores principales: Dubourg, Grégory, Lagier, Jean-Christophe, Brouqui, Philippe, Casalta, Jean-Paul, Jacomo, Véronique, La Scola, Bernard, Rolain, Jean-Marc, Raoult, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881284/
https://www.ncbi.nlm.nih.gov/pubmed/33632620
http://dx.doi.org/10.1016/j.jmii.2021.01.012
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author Dubourg, Grégory
Lagier, Jean-Christophe
Brouqui, Philippe
Casalta, Jean-Paul
Jacomo, Véronique
La Scola, Bernard
Rolain, Jean-Marc
Raoult, Didier
author_facet Dubourg, Grégory
Lagier, Jean-Christophe
Brouqui, Philippe
Casalta, Jean-Paul
Jacomo, Véronique
La Scola, Bernard
Rolain, Jean-Marc
Raoult, Didier
author_sort Dubourg, Grégory
collection PubMed
description Among 275 patients with COVID-19, we found that median blood zinc level was significantly lower in patients with poor clinical outcome (N = 75) as compared to patients with good clinical outcome (N = 200) (840 μg/L versus 970 μg/L; p < 0.0001), suggesting that zinc supplementation could be useful for patients with severe COVID-19.
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spelling pubmed-78812842021-02-16 Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients? Dubourg, Grégory Lagier, Jean-Christophe Brouqui, Philippe Casalta, Jean-Paul Jacomo, Véronique La Scola, Bernard Rolain, Jean-Marc Raoult, Didier J Microbiol Immunol Infect Short Communication Among 275 patients with COVID-19, we found that median blood zinc level was significantly lower in patients with poor clinical outcome (N = 75) as compared to patients with good clinical outcome (N = 200) (840 μg/L versus 970 μg/L; p < 0.0001), suggesting that zinc supplementation could be useful for patients with severe COVID-19. Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC. 2021-10 2021-02-13 /pmc/articles/PMC7881284/ /pubmed/33632620 http://dx.doi.org/10.1016/j.jmii.2021.01.012 Text en © 2021 Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Dubourg, Grégory
Lagier, Jean-Christophe
Brouqui, Philippe
Casalta, Jean-Paul
Jacomo, Véronique
La Scola, Bernard
Rolain, Jean-Marc
Raoult, Didier
Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients?
title Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients?
title_full Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients?
title_fullStr Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients?
title_full_unstemmed Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients?
title_short Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients?
title_sort low blood zinc concentrations in patients with poor clinical outcome during sars-cov-2 infection: is there a need to supplement with zinc covid-19 patients?
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881284/
https://www.ncbi.nlm.nih.gov/pubmed/33632620
http://dx.doi.org/10.1016/j.jmii.2021.01.012
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