Overexpression of Substance P in pig airways increases MUC5AC through an NF‐kβ pathway

Substance P (SP) is a tachykinin that regulates airway mucous secretion in both health and disease. Our study aimed to determine whether overexpression of SP without pre‐existing inflammation was sufficient to induce changes in mucin secretion and transport in small airways. Utilizing porcine precis...

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Detalles Bibliográficos
Autores principales: Sponchiado, Mariana, Liao, Yan‐Shin, Atanasova, Kalina R., Collins, Emily N., Schurmann, Veronica, Bravo, Laura, Reznikov, Leah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881348/
https://www.ncbi.nlm.nih.gov/pubmed/33580593
http://dx.doi.org/10.14814/phy2.14749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881348/
https://www.ncbi.nlm.nih.gov/pubmed/33580593
http://dx.doi.org/10.14814/phy2.14749

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