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Overexpression of Substance P in pig airways increases MUC5AC through an NF‐kβ pathway
Substance P (SP) is a tachykinin that regulates airway mucous secretion in both health and disease. Our study aimed to determine whether overexpression of SP without pre‐existing inflammation was sufficient to induce changes in mucin secretion and transport in small airways. Utilizing porcine precis...
Autores principales: | Sponchiado, Mariana, Liao, Yan‐Shin, Atanasova, Kalina R., Collins, Emily N., Schurmann, Veronica, Bravo, Laura, Reznikov, Leah R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881348/ https://www.ncbi.nlm.nih.gov/pubmed/33580593 http://dx.doi.org/10.14814/phy2.14749 |
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