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ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in non-melanoma skin cancers
BACKGROUND: p63, a member of the p53 gene family, is an important regulator for epithelial tissue growth and development. ∆Np63α is the main isoform of p63 and highly expressed in Non-melanoma skin cancer (NMSC). Extracellular signal-regulated kinase 3 (ERK3) is an atypical mitogen-activated protein...
Autores principales: | Alshammari, Eid S., Aljagthmi, Amjad A., Stacy, Andrew J., Bottomley, Mike, Shamma, H. Nicholas, Kadakia, Madhavi P., Long, Weiwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881562/ https://www.ncbi.nlm.nih.gov/pubmed/33579235 http://dx.doi.org/10.1186/s12885-021-07866-w |
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