FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer: rationale for a triple blockade of ER, CDK4/6, and FGFR1

BACKGROUND: FGFR1 amplification, but not overexpression, has been related to adverse prognosis in hormone-positive breast cancer (HRPBC). Whether FGFR1 overexpression and amplification are correlated, what is their distribution among luminal A or B HRPBC, and if there is a potential different progno...

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Detalles Bibliográficos
Autores principales: Mouron, Silvana, Manso, Luis, Caleiras, Eduardo, Rodriguez-Peralto, Jose L., Rueda, Oscar M., Caldas, Carlos, Colomer, Ramon, Quintela-Fandino, Miguel, Bueno, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881584/
https://www.ncbi.nlm.nih.gov/pubmed/33579347
http://dx.doi.org/10.1186/s13058-021-01398-8

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