Cargando…

The role of ARHGAP9: clinical implication and potential function in acute myeloid leukemia

BACKGROUND: Rho GTPase activating protein 9 (ARHGAP9) is expressed in various types of cancers and can inactivate Rho GTPases that mainly regulate cytoskeletal dynamics. However, the exact role of ARHGAP9 in acute myeloid leukemia (AML) has yet to be clarified. METHODS: We compared the transcription...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Caixia, He, Shujiao, Wang, Ruiqi, Gao, Xuefeng, Wang, Hong, Qiao, Jingqiao, Meng, Xiangyu, Li, Yonghui, Yu, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881617/ https://www.ncbi.nlm.nih.gov/pubmed/33579308 http://dx.doi.org/10.1186/s12967-021-02733-5

Ejemplares similares

Antigen-Specific TCR-T Cells for Acute Myeloid Leukemia: State of the Art and Challenges
por: Kang, Synat, et al.
Publicado: (2022)

Characteristics of Cohesin Mutation in Acute Myeloid Leukemia and Its Clinical Significance
por: Han, Caixia, et al.
Publicado: (2021)

A novel immune-related gene signature predicts the prognosis of hepatocellular carcinoma
por: He, Shujiao, et al.
Publicado: (2022)

Epigenetic silencing of UBXN8 contributes to leukemogenesis in t(8;21) acute myeloid leukemia
por: Yang, Erna, et al.
Publicado: (2021)

ADAMTS14, ARHGAP22, and EPDR1 as potential novel targets in acute myeloid leukaemia
por: El-Masry, Omar S., et al.
Publicado: (2022)

Evaluation of acute myeloid leukemia blast percentage on MethylC-Capture Sequencing results
por: Yang, Erna, et al.
Publicado: (2021)

Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia
por: Li, Yan, et al.
Publicado: (2017)

Clinical Benefits and Safety of Gemtuzumab Ozogamicin in Treating Acute Myeloid Leukemia in Various Subgroups: An Updated Systematic Review, Meta-Analysis, and Network Meta-Analysis
por: Xu, Qingyu, et al.
Publicado: (2021)

HNRNPL Circularizes ARHGAP35 to Produce an Oncogenic Protein
por: Li, Yan, et al.
Publicado: (2021)

Clinical Benefits and Safety of FMS-Like Tyrosine Kinase 3 Inhibitors in Various Treatment Stages of Acute Myeloid Leukemia: A Systematic Review, Meta-Analysis, and Network Meta-Analysis
por: Xu, Qingyu, et al.
Publicado: (2021)

DNA methylation landscape reveals LIN7A as a decitabine-responsive marker in patients with t(8;21) acute myeloid leukemia
por: He, Shujiao, et al.
Publicado: (2023)

Pan‑cancer analysis identified ARHGAP23 as a potential biomarker for pancreatic adenocarcinoma
por: Liu, Xiaolong, et al.
Publicado: (2023)

p190RhoGAPs, the ARHGAP35- and ARHGAP5-Encoded Proteins, in Health and Disease
por: Héraud, Capucine, et al.
Publicado: (2019)

Ginsenoside Rg3 inhibits the migration and invasion of liver cancer cells by increasing the protein expression of ARHGAP9
por: Sun, Meng-Yao, et al.
Publicado: (2019)

Clinical implication and potential function of ARHGEF6 in acute myeloid leukemia: An in vitro study
por: Li, Kang, et al.
Publicado: (2023)

Bioinformatics analysis of potential therapeutic targets among ARHGAP genes in breast cancer
por: Chen, Wei-Xian, et al.
Publicado: (2019)

Roles of Histone Deacetylases in Acute Myeloid Leukemia With Fusion Proteins
por: Zhang, Juan, et al.
Publicado: (2021)

ARHGAP9 suppresses the migration and invasion of hepatocellular carcinoma cells through up-regulating FOXJ2/E-cadherin
por: Zhang, Hong, et al.
Publicado: (2018)

CD9, a potential leukemia stem cell marker, regulates drug resistance and leukemia development in acute myeloid leukemia
por: Liu, Yongliang, et al.
Publicado: (2021)

Association of ARHGAP18 polymorphisms with schizophrenia in the Chinese-Han population
por: Guo, Weiyun, et al.
Publicado: (2017)

The prognostic impact of tet oncogene family member 2 mutations in patients with acute myeloid leukemia: a systematic-review and meta-analysis
por: Wang, Ruiqi, et al.
Publicado: (2019)

A novel tumor suppressing gene, ARHGAP9, is an independent prognostic biomarker for bladder cancer
por: Piao, Xuan-Mei, et al.
Publicado: (2020)

RhoA/ROCK/ARHGAP26 signaling in the eutopic and ectopic endometrium is involved in clinical characteristics of adenomyosis
por: Jiang, Caixia, et al.
Publicado: (2018)

Bimodal antagonism of PKA signalling by ARHGAP36
por: Eccles, Rebecca L., et al.
Publicado: (2016)

Hematopoietic defects in response to reduced Arhgap21
por: Xavier-Ferrucio, Juliana, et al.
Publicado: (2017)

Expression patterns of immune checkpoints in acute myeloid leukemia
por: Chen, Cunte, et al.
Publicado: (2020)

Decitabine-based chemotherapy followed by haploidentical lymphocyte infusion improves the effectiveness in elderly patients with acute myeloid leukemia
por: Jing, Yu, et al.
Publicado: (2016)

The role of GTPase-activating protein ARHGAP26 in human cancers
por: Zhang, Lingye, et al.
Publicado: (2021)

Protooncogenic Role of ARHGAP11A and ARHGAP11B in Invasive Ductal Carcinoma: Two Promising Breast Cancer Biomarkers
por: Naeimzadeh, Y., et al.
Publicado: (2023)

Regulation of ARHGAP19 in the endometrial epithelium: a possible role in the establishment of uterine receptivity
por: Liang, Jingjie, et al.
Publicado: (2021)

ARHGAP39 is a prognostic biomarker involved in immune infiltration in breast cancer
por: Yao, Litong, et al.
Publicado: (2023)

Prognostic impact of MYH9 expression on patients with acute myeloid leukemia
por: Yu, Mengxia, et al.
Publicado: (2016)

miR-939-5p Contributes to the Migration and Invasion of Pancreatic Cancer by Targeting ARHGAP4
por: Shen, Yehua, et al.
Publicado: (2020)

Identification of a novel gene fusion (BMX-ARHGAP) in gastric cardia adenocarcinoma
por: Xu, Xiaofeng, et al.
Publicado: (2014)

CDK9 inhibitors in acute myeloid leukemia
por: Boffo, Silvia, et al.
Publicado: (2018)

Prognostic nomogram for adult patients with acute myeloid leukemia: A SEER database analysis
por: Chen, Cunte, et al.
Publicado: (2019)

ARHGAP22 Localizes at Endosomes and Regulates Actin Cytoskeleton
por: Mori, Mamiko, et al.
Publicado: (2014)

SIRT1 suppresses the migration and invasion of gastric cancer by regulating ARHGAP5 expression
por: Dong, Guoying, et al.
Publicado: (2018)

DNA methylation of ARHGAP30 is negatively associated with ARHGAP30 expression in lung adenocarcinoma, which reduces tumor immunity and is detrimental to patient survival
por: Hu, Sheng, et al.
Publicado: (2021)

Acute Myeloid Leukemia Mutations: Therapeutic Implications
por: Papayannidis, Cristina, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_b9e398f2fruergtig1h2dc9130