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Multiple-testing correction in metabolome-wide association studies

BACKGROUND: The search for statistically significant relationships between molecular markers and outcomes is challenging when dealing with high-dimensional, noisy and collinear multivariate omics data, such as metabolomic profiles. Permutation procedures allow for the estimation of adjusted signific...

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Detalles Bibliográficos
Autores principales:	Peluso, Alina, Glen, Robert, Ebbels, Timothy M. D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881646/ https://www.ncbi.nlm.nih.gov/pubmed/33579202 http://dx.doi.org/10.1186/s12859-021-03975-2

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