SARS-CoV-2 Infects Human Pluripotent Stem Cell-Derived Cardiomyocytes, Impairing Electrical and Mechanical Function

COVID-19 patients often develop severe cardiovascular complications, but it remains unclear if these are caused directly by viral infection or are secondary to a systemic response. Here, we examine the cardiac tropism of SARS-CoV-2 in human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) and...

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Detalles Bibliográficos
Autores principales: Marchiano, Silvia, Hsiang, Tien-Ying, Khanna, Akshita, Higashi, Ty, Whitmore, Leanne S., Bargehr, Johannes, Davaapil, Hongorzul, Chang, Jean, Smith, Elise, Ong, Lay Ping, Colzani, Maria, Reinecke, Hans, Yang, Xiulan, Pabon, Lil, Sinha, Sanjay, Najafian, Behzad, Sniadecki, Nathan J., Bertero, Alessandro, Gale, Michael, Murry, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881699/
https://www.ncbi.nlm.nih.gov/pubmed/33657418
http://dx.doi.org/10.1016/j.stemcr.2021.02.008

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