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Aberrant Hypermethylation-Mediated Suppression of PYCARD Is Extremely Frequent in Prostate Cancer with Gleason Score ≥ 7

Epigenetic gene silencing by aberrant DNA methylation leads to loss of key cellular pathways in tumorigenesis. In order to analyze the effects of DNA methylation on prostate cancer, we established LNCaP-derived human prostate cancer cells that can pharmacologically induce global reactivation of hype...

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Detalles Bibliográficos
Autores principales:	Miyauchi, Toshiya, Takahashi, Masahiro, Mitsuzuka, Koji, Saiki, Yuriko, Okubo, Teppei, Vertino, Paula M., Goto, Akiteru, Arai, Yoichi, Horii, Akira, Fukushige, Shinichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881737/ https://www.ncbi.nlm.nih.gov/pubmed/33628338 http://dx.doi.org/10.1155/2021/8858905

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