Cargando…
XPR1 Mediates the Pancreatic β-Cell Phosphate Flush
Glucose-stimulated insulin secretion is the hallmark of the pancreatic β-cell, a critical player in the regulation of blood glucose concentration. In 1974, the remarkable observation was made that an efflux of intracellular inorganic phosphate (P(i)) accompanied the events of stimulated insulin secr...
Autores principales: | Barker, Christopher J., Tessaro, Fernando Henrique Galvão, Ferreira, Sabrina de Souza, Simas, Rafael, Ayala, Thais S., Köhler, Martin, Rajasekaran, Subu Surendran, Martins, Joilson O., Darè, Elisabetta, Berggren, Per-Olof |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881847/ https://www.ncbi.nlm.nih.gov/pubmed/32826297 http://dx.doi.org/10.2337/db19-0633 |
Ejemplares similares
-
Protein kinase- and lipase inhibitors of inositide metabolism deplete IP(7) indirectly in pancreatic β-cells: Off-target effects on cellular bioenergetics and direct effects on IP6K activity
por: Rajasekaran, Subu Surendran, et al.
Publicado: (2018) -
Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet
por: Molina, Judith, et al.
Publicado: (2014) -
Inositol hexakisphosphate kinase 1 is a metabolic sensor in pancreatic β-cells
por: Rajasekaran, Subu Surendran, et al.
Publicado: (2018) -
Corrigendum to ‘Inositol hexakisphosphate kinase 1 is a metabolic sensor in pancreatic β-cells’ [Cellular Signalling 46 (2018) 120–128]
por: Rajasekaran, Subu Surendran, et al.
Publicado: (2019) -
Mitochondrial GTP Insensitivity Contributes to Hypoglycemia in Hyperinsulinemia Hyperammonemia by Inhibiting Glucagon Release
por: Kibbey, Richard G., et al.
Publicado: (2014)