Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice

Protein citrullination plays a role in several autoimmune diseases. Its involvement in murine and human type 1 diabetes has recently been recognized through the discovery of antibodies and T-cell reactivity against citrullinated peptides. In the current study, we demonstrate that systemic inhibition...

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Detalles Bibliográficos
Autores principales: Sodré, Fernanda M.C., Bissenova, Samal, Bruggeman, Ylke, Tilvawala, Ronak, Cook, Dana P., Berthault, Claire, Mondal, Santanu, Callebaut, Aïsha, You, Sylvaine, Scharfmann, Raphael, Mallone, Roberto, Thompson, Paul R., Mathieu, Chantal, Buitinga, Mijke, Overbergh, Lut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881854/
https://www.ncbi.nlm.nih.gov/pubmed/33203696
http://dx.doi.org/10.2337/db20-0421

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