Relative Adipose Tissue Failure in Alström Syndrome Drives Obesity-Induced Insulin Resistance

Obesity is a major risk factor for insulin resistance (IR) and its attendant complications. The pathogenic mechanisms linking them remain poorly understood, partly due to a lack of intermediary monogenic human phenotypes. Here, we report on a monogenic form of IR-prone obesity, Alström syndrome (ALM...

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Detalles Bibliográficos
Autores principales: Geberhiwot, Tarekegn, Baig, Shanat, Obringer, Cathy, Girard, Dorothée, Dawson, Charlotte, Manolopoulos, Konstantinos, Messaddeq, Nadia, Bel Lassen, Pierre, Clement, Karine, Tomlinson, Jeremy W., Steeds, Richard P., Dollfus, Hélène, Petrovsky, Nikolai, Marion, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881858/
https://www.ncbi.nlm.nih.gov/pubmed/32994277
http://dx.doi.org/10.2337/db20-0647

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