Epigenome screening highlights that JMJD6 confers an epigenetic vulnerability and mediates sunitinib sensitivity in renal cell carcinoma

Aberrant epigenetic reprogramming represents a hallmark of renal cell carcinoma (RCC) tumorigenesis and progression. Whether there existed other epigenetic vulnerabilities that could serve as therapeutic targets remained unclear and promising. Here, we combined the clustered regularly interspaced sh...

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Detalles Bibliográficos
Autores principales: Zhang, Chuanjie, Lu, Xuan, Huang, Jingyi, He, Hongchao, Chen, Li, Liu, Yihan, Wang, Haofei, Xu, Yang, Xing, Siwei, Ruan, Xiaohao, Yang, Xiaoqun, Chen, Lu, Xu, Danfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882098/
https://www.ncbi.nlm.nih.gov/pubmed/33634984
http://dx.doi.org/10.1002/ctm2.328

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