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The CB1R rs2023239 receptor gene variant significantly affects the reinforcing effects of nicotine, but not cue reactivity, in human smokers

INTRODUCTION: The cannabinoid CB1 receptor (CB1R) has been shown in preclinical studies to be involved in nicotine reinforcement and relapse‐like behavior. The common single nucleotide polymorphism (SNP) rs2023239 may code for an alternative CB1R protein, alter CB1R expression, and be involved in ni...

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Detalles Bibliográficos
Autores principales:	Chukwueke, Chidera C., Kowalczyk, William J., Gendy, Marie, Taylor, Richard, Tyndale, Rachel F., Le Foll, Bernard, Heishman, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882168/ https://www.ncbi.nlm.nih.gov/pubmed/33369277 http://dx.doi.org/10.1002/brb3.1982

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