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Functional inhibition of heat shock protein 70 by VER‐155008 suppresses pleural mesothelioma cell proliferation via an autophagy mechanism
Background: Pleural mesothelioma, a devastating asbestos‐associated malignancy, urgently requires a novel effective therapy. Heat shock protein 70 (HSP70), which is synthesized in the cell response to protein damage, is expected to be a new target for antitumor treatment. In addition to its well‐kno...
Autores principales: | Sakai, Kosuke, Inoue, Maya, Mikami, Shintaro, Nishimura, Hiroaki, Kuwabara, Yoshiki, Kojima, Akitoshi, Toda, Maiko, Ogawa‐Kobayashi, Yumiko, Kikuchi, Satoshi, Hirata, Yusuke, Mikami‐Saito, Yuriko, Kyoyama, Hiroyuki, Moriyama, Gaku, Shiibashi, Michio, Seike, Masahiro, Gemma, Akihiko, Uematsu, Kazutsugu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882380/ https://www.ncbi.nlm.nih.gov/pubmed/33319489 http://dx.doi.org/10.1111/1759-7714.13784 |
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