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EMT-independent detection of circulating tumor cells in human blood samples and pre-clinical mouse models of metastasis

Circulating tumor cells (CTCs) present an opportunity to detect/monitor metastasis throughout disease progression. The CellSearch® is currently the only FDA-approved technology for CTC detection in patients. The main limitation of this system is its reliance on epithelial markers for CTC isolation/e...

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Detalles Bibliográficos
Autores principales: Kitz, Jenna, Goodale, David, Postenka, Carl, Lowes, Lori E., Allan, Alison L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882592/
https://www.ncbi.nlm.nih.gov/pubmed/33415568
http://dx.doi.org/10.1007/s10585-020-10070-y