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ALMS1 Regulates TGF-β Signaling and Morphology of Primary Cilia

In this study, we aimed to evaluate the role of ALMS1 in the morphology of primary cilia and regulation of cellular signaling using a knockdown model of the hTERT-RPE1 cell line. ALMS1 depletion resulted in the formation of longer cilia, which often displayed altered morphology as evidenced by exten...

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Detalles Bibliográficos
Autores principales: Álvarez-Satta, María, Lago-Docampo, Mauro, Bea-Mascato, Brais, Solarat, Carlos, Castro-Sánchez, Sheila, Christensen, Søren T., Valverde, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882606/
https://www.ncbi.nlm.nih.gov/pubmed/33598462
http://dx.doi.org/10.3389/fcell.2021.623829

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