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ALMS1 Regulates TGF-β Signaling and Morphology of Primary Cilia
In this study, we aimed to evaluate the role of ALMS1 in the morphology of primary cilia and regulation of cellular signaling using a knockdown model of the hTERT-RPE1 cell line. ALMS1 depletion resulted in the formation of longer cilia, which often displayed altered morphology as evidenced by exten...
Autores principales: | Álvarez-Satta, María, Lago-Docampo, Mauro, Bea-Mascato, Brais, Solarat, Carlos, Castro-Sánchez, Sheila, Christensen, Søren T., Valverde, Diana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882606/ https://www.ncbi.nlm.nih.gov/pubmed/33598462 http://dx.doi.org/10.3389/fcell.2021.623829 |
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