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Induced Arp2/3 Complex Depletion Increases FMNL2/3 Formin Expression and Filopodia Formation

The Arp2/3 complex generates branched actin filament networks operating in cell edge protrusion and vesicle trafficking. Here we employ a conditional knockout mouse model permitting tissue- or cell-type specific deletion of the murine Actr3 gene (encoding Arp3). A functional Actr3 gene appeared esse...

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Detalles Bibliográficos
Autores principales:	Dimchev, Vanessa, Lahmann, Ines, Koestler, Stefan A., Kage, Frieda, Dimchev, Georgi, Steffen, Anika, Stradal, Theresia E. B., Vauti, Franz, Arnold, Hans-Henning, Rottner, Klemens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882613/ https://www.ncbi.nlm.nih.gov/pubmed/33598464 http://dx.doi.org/10.3389/fcell.2021.634708

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