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Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits

A greater understanding of the genes involved in antibiotic resistance in Mycobacterium tuberculosis (Mtb) is necessary for the design of improved therapies. Clustered regularly interspaced short palindromic repeat interference (CRISPRi) has been previously utilized in mycobacteria to identify novel...

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Detalles Bibliográficos
Autores principales:	Faulkner, Valwynne, Cox, Adrienne Adele, Goh, Shan, van Bohemen, Annelies, Gibson, Amanda J., Liebster, Oliver, Wren, Brendan W., Willcocks, Sam, Kendall, Sharon L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882622/ https://www.ncbi.nlm.nih.gov/pubmed/33597931 http://dx.doi.org/10.3389/fmicb.2020.619427

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