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Propranolol Sensitizes Vascular Sarcoma Cells to Doxorubicin by Altering Lysosomal Drug Sequestration and Drug Efflux
Angiosarcoma is a rare cancer of blood vessel–forming cells with a high patient mortality and few treatment options. Although chemotherapy often produces initial clinical responses, outcomes remain poor, largely due to the development of drug resistance. We previously identified a subset of doxorubi...
Autores principales: | Saha, Jhuma, Kim, Jong Hyuk, Amaya, Clarissa N., Witcher, Caleb, Khammanivong, Ali, Korpela, Derek M., Brown, David R., Taylor, Josephine, Bryan, Brad A., Dickerson, Erin B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882688/ https://www.ncbi.nlm.nih.gov/pubmed/33598432 http://dx.doi.org/10.3389/fonc.2020.614288 |
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