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Downregulation of CISD2 Has Prognostic Value in Non-Small Cell Lung Cancer and Inhibits the Tumorigenesis by Inducing Mitochondrial Dysfunction

CISD2, a NEET protein that coordinates 2Fe-2S clusters through its CDGSH domain, is critical for normal development and iron homeostasis. CISD2 plays an important role in Fe-S cluster transfer and promotes cancer proliferation. However, its specific role in the development of non-small cell lung can...

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Detalles Bibliográficos
Autores principales: Shao, Fangchun, Li, Yanchun, Hu, Wanye, Yu, Jiaqi, Wu, HengYu, Ying, Kejing, Xia, Jun, Du, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882736/
https://www.ncbi.nlm.nih.gov/pubmed/33598426
http://dx.doi.org/10.3389/fonc.2020.595524