Cargando…

Long non‐coding RNA MEG3 silencing and microRNA‐214 restoration elevate osteoprotegerin expression to ameliorate osteoporosis by limiting TXNIP

Studies have shown that long non‐coding RNA (lncRNA) MEG3 plays a key role in osteoporosis (OP), but its regulatory mechanism is somewhat incompletely clear. Here, we intend to probe into the mechanism of MEG3 on OP development by modulating microRNA‐214 (miR‐214) and thioredoxin‐interacting protein...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, ChangSheng, Gu, ZhengTao, Ding, Rui, Huang, CaiQiang, Li, QingChu, Xie, DengHui, Zhang, RongKai, Qiu, YiYan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882928/ https://www.ncbi.nlm.nih.gov/pubmed/33393160 http://dx.doi.org/10.1111/jcmm.16096

Ejemplares similares

PAX8-AS1 knockdown facilitates cell growth and inactivates autophagy in osteoblasts via the miR-1252-5p/GNB1 axis in osteoporosis
por: Huang, Caiqiang, et al.
Publicado: (2021)

MicroRNA‐497 elevation or LRG1 knockdown promotes osteoblast proliferation and collagen synthesis in osteoporosis via TGF‐β1/Smads signalling pathway
por: Gu, ZhengTao, et al.
Publicado: (2020)

GPR173 agonist phoenixin 20 promotes osteoblastic differentiation of MC3T3-E1 cells
por: Gu, Zhengtao, et al.
Publicado: (2020)

Preliminary outcomes of allograft and hydroxyapatite as substitutes for autograft in anterior cervical discectomy and fusion with self-locking standalone cages
por: Yang, Changsheng, et al.
Publicado: (2021)

LncRNA PVT1 promotes ovarian cancer progression by silencing miR-214
por: Chen, Ying, et al.
Publicado: (2018)

Effects of siRNA silencing on the susceptibility of the fish cell line CHSE-214 to Yersinia ruckeri
por: Menanteau-Ledouble, Simon, et al.
Publicado: (2020)

lncRNA MEG3 promotes hepatic insulin resistance by serving as a competing endogenous RNA of miR-214 to regulate ATF4 expression
por: Zhu, Xiang, et al.
Publicado: (2019)

Adenovirus-associated anti-miRNA-214 regulates bone metabolism and prevents local osteoporosis in rats
por: Wang, Cheng, et al.
Publicado: (2023)

MicroRNA-214 in Health and Disease
por: Amin, Meer M. J., et al.
Publicado: (2021)

Osteoporosis and polymorphisms of osteoprotegerin gene in postmenopausal women – a pilot study
por: Cvijetic, Selma, et al.
Publicado: (2016)

The association of osteoprotegerin and RANKL with osteoporosis: a systematic review with meta-analysis
por: Chi, Guanghao, et al.
Publicado: (2023)

Cutting Calories and TXNIP From the Skeletal Muscle to Restore Insulin Sensitivity
por: Anderson, Ethan J.
Publicado: (2016)

Screening of osteoprotegerin-related feature genes in osteoporosis and functional analysis with DNA microarray
por: Wu, Xiaoming, et al.
Publicado: (2013)

The inhibitory effect of MEG3/miR-214/AIFM2 axis on the growth of T-cell lymphoblastic lymphoma
por: Fan, Fang-Yi, et al.
Publicado: (2020)

New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats
por: Ding, Chunchun, et al.
Publicado: (2016)

Eurycoma longifolia upregulates osteoprotegerin gene expression in androgen- deficient osteoporosis rat model
por: Shuid, Ahmad Nazrun, et al.
Publicado: (2012)

Exercise training restores the cardiac microRNA-1 and −214 levels regulating Ca(2+) handling after myocardial infarction
por: Melo, Stéphano Freitas Soares, et al.
Publicado: (2015)

Silencing Of Circular RNA-ZNF609 Ameliorates Vascular Endothelial Dysfunction
por: Liu, Chang, et al.
Publicado: (2017)

microRNA-214-mediated UBC9 expression in glioma
por: Zhao, Zhiqiang, et al.
Publicado: (2012)

Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice
por: Okada, Hikari, et al.
Publicado: (2015)

LncRNA-MIAT-Mediated miR-214-3p Silencing Is Responsible for IL-17 Production and Cardiac Fibrosis in Diabetic Cardiomyopathy
por: Qi, Yanqing, et al.
Publicado: (2020)

Silencing Of hsa_circ_0008450 Represses Hepatocellular Carcinoma Progression Through Regulation Of microRNA-214-3p/EZH2 Axis
por: Lin, Tianyu, et al.
Publicado: (2019)

Osteoprotegerin Polymorphisms in a Mexican Population with Rheumatoid Arthritis and Generalized Osteoporosis: A Preliminary Report
por: Zavala-Cerna, Maria Guadalupe, et al.
Publicado: (2015)

Silencing long non‐coding RNA MEG3 accelerates tibia fraction healing by regulating the Wnt/β‐catenin signalling pathway
por: Liu, Yu‐Bao, et al.
Publicado: (2019)

MicroRNA-214 and MicroRNA-126 Are Potential Biomarkers for Malignant Endothelial Proliferative Diseases
por: Heishima, Kazuki, et al.
Publicado: (2015)

MicroRNA-214-5p/TGF-β/Smad2 signaling alters adipogenic differentiation of bone marrow stem cells in postmenopausal osteoporosis
por: Qiu, Jiang, et al.
Publicado: (2018)

N-Lobe of TXNIP Is Critical in the Allosteric Regulation of NLRP3 via TXNIP Binding
por: Cheng, Fengyu, et al.
Publicado: (2022)

Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus mice
por: Garchow, Barry G, et al.
Publicado: (2011)

T-Cell–Derived miRNA-214 Mediates Perivascular Fibrosis in Hypertension
por: Nosalski, Ryszard, et al.
Publicado: (2020)

Restoring the Long Noncoding RNA MEG3 Indicates a Potential Role for JAK-STAT Signaling in Chronic Myeloid Leukemia
por: Olson, Thomas L., et al.
Publicado: (2018)

Role of Serum Osteoprotegerin as a Diagnostic Indicator of Primary Osteoporosis in Perimenopausal and Postmenopausal Women: An Indian Perspective
por: Pandey, A, et al.
Publicado: (2018)

Osthole enhances the bone mass of senile osteoporosis and stimulates the expression of osteoprotegerin by activating β-catenin signaling
por: Jin, Zhen-Xiong, et al.
Publicado: (2021)

Therapeutic implications of osteoprotegerin
por: Fili, Sofia, et al.
Publicado: (2009)

The role of osteoprotegerin in arthritis
por: Schett, Georg, et al.
Publicado: (2003)

Osteoprotegerin in Cardiometabolic Disorders
por: Pérez de Ciriza, C., et al.
Publicado: (2015)

Long Non-Coding RNA MEG3 in Cellular Stemness
por: Hsieh, Pei-Fang, et al.
Publicado: (2021)

Long Non-Coding RNA MEG3 in Metal Carcinogenesis
por: Zhang, Zhuo, et al.
Publicado: (2023)

Induction of microRNA-214-5p in human and rodent liver fibrosis
por: Iizuka, Masashi, et al.
Publicado: (2012)

Resistance Training Regulates Cardiac Function through Modulation of miRNA-214
por: Melo, Stéphano Freitas Soares, et al.
Publicado: (2015)

Dysregulation of microRNA-214 and PTEN contributes to the pathogenesis of hypoxic pulmonary hypertension
por: Liu, HaiTao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_prsbumthhbo5qjerho36jbpd39