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Potency, Safety, and Pharmacokinetic Profiles of Potential Inhibitors Targeting SARS-CoV-2 Main Protease

Effective, safe, and pharmacokinetically suitable drugs are urgently needed to curb the ongoing COVID-19 pandemic. The main protease or 3C-like protease (M(pro) or 3CL(pro)) of SARS-CoV-2 is considered an important target to formulate potent drugs corresponding to its crucial role in virus replicati...

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Detalles Bibliográficos
Autores principales:	Mengist, Hylemariam Mihiretie, Mekonnen, Daniel, Mohammed, Ahmed, Shi, Ronghua, Jin, Tengchuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883113/ https://www.ncbi.nlm.nih.gov/pubmed/33597888 http://dx.doi.org/10.3389/fphar.2020.630500

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