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Routine Measurement of Thyroid Stimulating Hormone in Patients Presenting With Third-Degree Atrioventricular Block: Do We Really Need It?

Background Hypothyroidism can be a cause of sinus bradycardia. However, thyroid laboratory evaluation is often performed routinely in patients with complete heart block (CHB) though there is little data to support this practice. This study aimed to assess the frequency of thyroid dysfunction in pati...

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Autores principales: Faisal, Muhammad, Mumtaz, Zubair, Mueed, Abdul, Ali, Sajid, Raza, Haseeb H, Khan, Samra, Salma, Sayeda, Mujtaba, Mustajab, Karim, Musa, Qadir, Faisal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883583/
https://www.ncbi.nlm.nih.gov/pubmed/33614317
http://dx.doi.org/10.7759/cureus.12712
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author Faisal, Muhammad
Mumtaz, Zubair
Mueed, Abdul
Ali, Sajid
Raza, Haseeb H
Khan, Samra
Salma, Sayeda
Mujtaba, Mustajab
Karim, Musa
Qadir, Faisal
author_facet Faisal, Muhammad
Mumtaz, Zubair
Mueed, Abdul
Ali, Sajid
Raza, Haseeb H
Khan, Samra
Salma, Sayeda
Mujtaba, Mustajab
Karim, Musa
Qadir, Faisal
author_sort Faisal, Muhammad
collection PubMed
description Background Hypothyroidism can be a cause of sinus bradycardia. However, thyroid laboratory evaluation is often performed routinely in patients with complete heart block (CHB) though there is little data to support this practice. This study aimed to assess the frequency of thyroid dysfunction in patients presenting with CHB without clinical features of hypothyroidism. Methodology All patients referred for permanent pacemaker implantation for CHB were included in this cross-sectional study. Patients with known thyroid disorder or clinical features of thyroid disorder were excluded. Demographic, electrocardiography (EKG), and routine thyroid stimulating hormone (TSH) screening results were recorded. Results A total of 102 patients with complete atrioventricular (AV) block were enrolled in the study of which 50.0% (51) were male. The mean age was 61.09 ± 11.74. Co-morbidities included diabetes mellitus 44.1% (45), smoking 36.3% (37), and hypertension 55.9% (57). Mean EKG atrial rate was 82.97 ± 31.31 mmHg with a mean ventricular escape rate of 36.17 ± 5.93. Permanent pacemakers were implanted in all of the patients. Only one patient had an abnormal TSH. Conclusions We found a very low prevalence of thyroid dysfunction among patients without clinical features of thyroid dysfunction presenting with third-degree AV block. This calls for cautious prescription of thyroid testing in clinically euthyroid patients.
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spelling pubmed-78835832021-02-18 Routine Measurement of Thyroid Stimulating Hormone in Patients Presenting With Third-Degree Atrioventricular Block: Do We Really Need It? Faisal, Muhammad Mumtaz, Zubair Mueed, Abdul Ali, Sajid Raza, Haseeb H Khan, Samra Salma, Sayeda Mujtaba, Mustajab Karim, Musa Qadir, Faisal Cureus Cardiology Background Hypothyroidism can be a cause of sinus bradycardia. However, thyroid laboratory evaluation is often performed routinely in patients with complete heart block (CHB) though there is little data to support this practice. This study aimed to assess the frequency of thyroid dysfunction in patients presenting with CHB without clinical features of hypothyroidism. Methodology All patients referred for permanent pacemaker implantation for CHB were included in this cross-sectional study. Patients with known thyroid disorder or clinical features of thyroid disorder were excluded. Demographic, electrocardiography (EKG), and routine thyroid stimulating hormone (TSH) screening results were recorded. Results A total of 102 patients with complete atrioventricular (AV) block were enrolled in the study of which 50.0% (51) were male. The mean age was 61.09 ± 11.74. Co-morbidities included diabetes mellitus 44.1% (45), smoking 36.3% (37), and hypertension 55.9% (57). Mean EKG atrial rate was 82.97 ± 31.31 mmHg with a mean ventricular escape rate of 36.17 ± 5.93. Permanent pacemakers were implanted in all of the patients. Only one patient had an abnormal TSH. Conclusions We found a very low prevalence of thyroid dysfunction among patients without clinical features of thyroid dysfunction presenting with third-degree AV block. This calls for cautious prescription of thyroid testing in clinically euthyroid patients. Cureus 2021-01-14 /pmc/articles/PMC7883583/ /pubmed/33614317 http://dx.doi.org/10.7759/cureus.12712 Text en Copyright © 2021, Faisal et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Faisal, Muhammad
Mumtaz, Zubair
Mueed, Abdul
Ali, Sajid
Raza, Haseeb H
Khan, Samra
Salma, Sayeda
Mujtaba, Mustajab
Karim, Musa
Qadir, Faisal
Routine Measurement of Thyroid Stimulating Hormone in Patients Presenting With Third-Degree Atrioventricular Block: Do We Really Need It?
title Routine Measurement of Thyroid Stimulating Hormone in Patients Presenting With Third-Degree Atrioventricular Block: Do We Really Need It?
title_full Routine Measurement of Thyroid Stimulating Hormone in Patients Presenting With Third-Degree Atrioventricular Block: Do We Really Need It?
title_fullStr Routine Measurement of Thyroid Stimulating Hormone in Patients Presenting With Third-Degree Atrioventricular Block: Do We Really Need It?
title_full_unstemmed Routine Measurement of Thyroid Stimulating Hormone in Patients Presenting With Third-Degree Atrioventricular Block: Do We Really Need It?
title_short Routine Measurement of Thyroid Stimulating Hormone in Patients Presenting With Third-Degree Atrioventricular Block: Do We Really Need It?
title_sort routine measurement of thyroid stimulating hormone in patients presenting with third-degree atrioventricular block: do we really need it?
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883583/
https://www.ncbi.nlm.nih.gov/pubmed/33614317
http://dx.doi.org/10.7759/cureus.12712
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