Cargando…
A Selective α7 Nicotinic Acetylcholine Receptor Agonist, PNU-282987, Attenuates ILC2s Activation and Alternaria-Induced Airway Inflammation
BACKGROUND: The anti-inflammatory effect of an α7nAChR agonist, PNU-282987, has previously been explored in the context of inflammatory disease. However, the effects of PNU-282987 on type 2 innate lymphoid cells (ILC2s)-mediated allergic airway inflammation has not yet been established. AIMS: To det...
Autores principales: | Yuan, Fang, Jiang, Lili, Li, Qianyang, Sokulsky, Leon, Wanyan, Yuanyuan, Wang, Lingli, Liu, Xiaojie, Zhou, Lujia, Tay, Hock L., Zhang, Guojun, Yang, Ming, Li, Fuguang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883686/ https://www.ncbi.nlm.nih.gov/pubmed/33597946 http://dx.doi.org/10.3389/fimmu.2020.598165 |
Ejemplares similares
-
α7 Nicotinic Acetylcholine Receptor Agonist PNU-282987 Ameliorates Cognitive Impairment Induced by Chronic Intermittent Hypoxia
por: Shen, Hui, et al.
Publicado: (2021) -
The α7 nicotinic acetylcholine receptor agonist PNU-282987 ameliorates sepsis-induced acute kidney injury through CD4(+)CD25(+) regulatory T cells in rats
por: Shi, Xiaocui, et al.
Publicado: (2022) -
Effect of Intrahippocampal Administration of α7 Subtype Nicotinic Receptor Agonist PNU-282987 and Its Solvent Dimethyl Sulfoxide on the Efficiency of Hypoxic Preconditioning in Rats
por: Zakharova, Elena I., et al.
Publicado: (2021) -
Protective Effect of the α7 Nicotinic Receptor Agonist PNU-282987 on Dopaminergic Neurons Against 6-Hydroxydopamine, Regulating Anti-neuroinflammatory and the Immune Balance Pathways in Rat
por: Jiang, Ying, et al.
Publicado: (2021) -
Combined administration of SHP2 inhibitor SHP099 and the α7nAChR agonist PNU282987 protect mice against DSS-induced colitis
por: Xiao, Junhua, et al.
Publicado: (2020)