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Generalized SIR (GSIR) epidemic model: An improved framework for the predictive monitoring of COVID-19 pandemic

Novel coronavirus respiratory disease COVID-19 has caused havoc in many countries across the globe. In order to contain infection of this highly contagious disease, most of the world population is constrained to live in a complete or partial lockdown for months together with a minimal human-to-human...

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Autores principales: Singh, Pushpendra, Gupta, Anubha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ISA. Published by Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883688/
https://www.ncbi.nlm.nih.gov/pubmed/33610314
http://dx.doi.org/10.1016/j.isatra.2021.02.016
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author Singh, Pushpendra
Gupta, Anubha
author_facet Singh, Pushpendra
Gupta, Anubha
author_sort Singh, Pushpendra
collection PubMed
description Novel coronavirus respiratory disease COVID-19 has caused havoc in many countries across the globe. In order to contain infection of this highly contagious disease, most of the world population is constrained to live in a complete or partial lockdown for months together with a minimal human-to-human interaction having far reaching consequences on countries’ economy and mental well-being of their citizens. Hence, there is a need for a good predictive model for the health advisory bodies and decision makers for taking calculated proactive measures to contain the pandemic and maintain a healthy economy. This paper extends the mathematical theory of the classical Susceptible–Infected–Removed (SIR) epidemic model and proposes a Generalized SIR (GSIR) model that is an integrative model encompassing multiple waves of daily reported cases. Existing growth function models of epidemic have been shown as the special cases of the GSIR model. Dynamic modeling of the parameters reflect the impact of policy decisions, social awareness, and the availability of medication during the pandemic. GSIR framework can be utilized to find a good fit or predictive model for any pandemic. The study is performed on the COVID-19 data for various countries with detailed results for India, Brazil, United States of America (USA), and World. The peak infection, total expected number of COVID-19 cases and thereof deaths, time-varying reproduction number, and various other parameters are estimated from the available data using the proposed methodology. The proposed GSIR model advances the existing theory and yields promising results for continuous predictive monitoring of COVID-19 pandemic.
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spelling pubmed-78836882021-02-16 Generalized SIR (GSIR) epidemic model: An improved framework for the predictive monitoring of COVID-19 pandemic Singh, Pushpendra Gupta, Anubha ISA Trans Research Article Novel coronavirus respiratory disease COVID-19 has caused havoc in many countries across the globe. In order to contain infection of this highly contagious disease, most of the world population is constrained to live in a complete or partial lockdown for months together with a minimal human-to-human interaction having far reaching consequences on countries’ economy and mental well-being of their citizens. Hence, there is a need for a good predictive model for the health advisory bodies and decision makers for taking calculated proactive measures to contain the pandemic and maintain a healthy economy. This paper extends the mathematical theory of the classical Susceptible–Infected–Removed (SIR) epidemic model and proposes a Generalized SIR (GSIR) model that is an integrative model encompassing multiple waves of daily reported cases. Existing growth function models of epidemic have been shown as the special cases of the GSIR model. Dynamic modeling of the parameters reflect the impact of policy decisions, social awareness, and the availability of medication during the pandemic. GSIR framework can be utilized to find a good fit or predictive model for any pandemic. The study is performed on the COVID-19 data for various countries with detailed results for India, Brazil, United States of America (USA), and World. The peak infection, total expected number of COVID-19 cases and thereof deaths, time-varying reproduction number, and various other parameters are estimated from the available data using the proposed methodology. The proposed GSIR model advances the existing theory and yields promising results for continuous predictive monitoring of COVID-19 pandemic. ISA. Published by Elsevier Ltd. 2022-05 2021-02-15 /pmc/articles/PMC7883688/ /pubmed/33610314 http://dx.doi.org/10.1016/j.isatra.2021.02.016 Text en © 2021 ISA. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Research Article
Singh, Pushpendra
Gupta, Anubha
Generalized SIR (GSIR) epidemic model: An improved framework for the predictive monitoring of COVID-19 pandemic
title Generalized SIR (GSIR) epidemic model: An improved framework for the predictive monitoring of COVID-19 pandemic
title_full Generalized SIR (GSIR) epidemic model: An improved framework for the predictive monitoring of COVID-19 pandemic
title_fullStr Generalized SIR (GSIR) epidemic model: An improved framework for the predictive monitoring of COVID-19 pandemic
title_full_unstemmed Generalized SIR (GSIR) epidemic model: An improved framework for the predictive monitoring of COVID-19 pandemic
title_short Generalized SIR (GSIR) epidemic model: An improved framework for the predictive monitoring of COVID-19 pandemic
title_sort generalized sir (gsir) epidemic model: an improved framework for the predictive monitoring of covid-19 pandemic
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883688/
https://www.ncbi.nlm.nih.gov/pubmed/33610314
http://dx.doi.org/10.1016/j.isatra.2021.02.016
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