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Computational analyses reveal spatial relationships between nuclear pore complexes and specific lamins

Nuclear lamin isoforms form fibrous meshworks associated with nuclear pore complexes (NPCs). Using datasets prepared from subpixel and segmentation analyses of 3D–structured illumination microscopy images of WT and lamin isoform knockout mouse embryo fibroblasts, we determined with high precision th...

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Detalles Bibliográficos
Autores principales: Kittisopikul, Mark, Shimi, Takeshi, Tatli, Meltem, Tran, Joseph Riley, Zheng, Yixian, Medalia, Ohad, Jaqaman, Khuloud, Adam, Stephen A., Goldman, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883741/
https://www.ncbi.nlm.nih.gov/pubmed/33570570
http://dx.doi.org/10.1083/jcb.202007082