Nuclear envelope lipids request border surveillance

In this issue, Thaller et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202004222) explore how the ESCRT protein Chm7 is recruited to sites of defective nuclear pore assembly. They show that a lipid, phosphatidic acid, is enriched at pathological nuclear envelope herniations, where it promote...

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Detalles Bibliográficos
Autor principal: Köhler, Alwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883742/
https://www.ncbi.nlm.nih.gov/pubmed/33599714
http://dx.doi.org/10.1083/jcb.202101164
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author Köhler, Alwin
author_facet Köhler, Alwin
author_sort Köhler, Alwin
collection PubMed
description In this issue, Thaller et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202004222) explore how the ESCRT protein Chm7 is recruited to sites of defective nuclear pore assembly. They show that a lipid, phosphatidic acid, is enriched at pathological nuclear envelope herniations, where it promotes Chm7 recruitment for membrane surveillance and repair.
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spelling pubmed-78837422021-09-01 Nuclear envelope lipids request border surveillance Köhler, Alwin J Cell Biol Spotlight In this issue, Thaller et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202004222) explore how the ESCRT protein Chm7 is recruited to sites of defective nuclear pore assembly. They show that a lipid, phosphatidic acid, is enriched at pathological nuclear envelope herniations, where it promotes Chm7 recruitment for membrane surveillance and repair. Rockefeller University Press 2021-02-11 /pmc/articles/PMC7883742/ /pubmed/33599714 http://dx.doi.org/10.1083/jcb.202101164 Text en © 2021 Köhler http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
Köhler, Alwin
Nuclear envelope lipids request border surveillance
title Nuclear envelope lipids request border surveillance
title_full Nuclear envelope lipids request border surveillance
title_fullStr Nuclear envelope lipids request border surveillance
title_full_unstemmed Nuclear envelope lipids request border surveillance
title_short Nuclear envelope lipids request border surveillance
title_sort nuclear envelope lipids request border surveillance
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883742/
https://www.ncbi.nlm.nih.gov/pubmed/33599714
http://dx.doi.org/10.1083/jcb.202101164
work_keys_str_mv AT kohleralwin nuclearenvelopelipidsrequestbordersurveillance

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