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Alogliptin Attenuates Lipopolysaccharide-Induced Neuroinflammation in Mice Through Modulation of TLR4/MYD88/NF-κB and miRNA-155/SOCS-1 Signaling Pathways

BACKGROUND: Endotoxin-induced neuroinflammation plays a crucial role in the pathogenesis and progression of various neurodegenerative diseases. A growing body of evidence supports that incretin-acting drugs possess various neuroprotective effects that can improve learning and memory impairments in A...

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Detalles Bibliográficos
Autores principales: El-Sahar, Ayman E, Shiha, Nesma A, El Sayed, Nesrine S, Ahmed, Lamiaa A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883892/
https://www.ncbi.nlm.nih.gov/pubmed/33125461
http://dx.doi.org/10.1093/ijnp/pyaa078