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Mass Generation, Neuron Labeling, and 3D Imaging of Minibrains

Minibrain is a 3D brain in vitro spheroid model, composed of a mixed population of neurons and glial cells, generated from human iPSC derived neural stem cells. Despite the advances in human 3D in vitro models such as aggregates, spheroids and organoids, there is a lack of labeling and imaging metho...

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Detalles Bibliográficos
Autores principales: Govindan, Subashika, Batti, Laura, Osterop, Samira F., Stoppini, Luc, Roux, Adrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883898/
https://www.ncbi.nlm.nih.gov/pubmed/33598450
http://dx.doi.org/10.3389/fbioe.2020.582650