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Targeting age‐specific changes in CD4(+) T cell metabolism ameliorates alloimmune responses and prolongs graft survival
Age impacts alloimmunity. Effects of aging on T‐cell metabolism and the potential to interfere with immunosuppressants have not been explored yet. Here, we dissected metabolic pathways of CD4(+) and CD8(+) T cells in aging and offer novel immunosuppressive targets. Upon activation, CD4(+) T cells fr...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884034/ https://www.ncbi.nlm.nih.gov/pubmed/33497523 http://dx.doi.org/10.1111/acel.13299 |