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COVID-19 lungs in post-mortem computed tomography

Post-mortem computed tomography (PMCT) is a rapid and noninvasive diagnostic tool for important contributions to the identification of pulmonary findings in the deceased with pneumonia, including cases of coronavirus disease 2019 (COVID-19). Although computed tomography (CT) shows a high sensitivity...

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Autores principales: Kniep, I., Heinemann, A., Edler, C., Sperhake, J. P., Püschel, K., Ondruschka, B., Schröder, A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884063/
https://www.ncbi.nlm.nih.gov/pubmed/33612977
http://dx.doi.org/10.1007/s00194-021-00462-z
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author Kniep, I.
Heinemann, A.
Edler, C.
Sperhake, J. P.
Püschel, K.
Ondruschka, B.
Schröder, A. S.
author_facet Kniep, I.
Heinemann, A.
Edler, C.
Sperhake, J. P.
Püschel, K.
Ondruschka, B.
Schröder, A. S.
author_sort Kniep, I.
collection PubMed
description Post-mortem computed tomography (PMCT) is a rapid and noninvasive diagnostic tool for important contributions to the identification of pulmonary findings in the deceased with pneumonia, including cases of coronavirus disease 2019 (COVID-19). Although computed tomography (CT) shows a high sensitivity for pneumonia in living persons, it is relatively unspecific for COVID-19 pneumonia clinically. Typical CT findings for viral pneumonia therefore require confirmation by PCR tests (polymerase chain reaction tests), even if lung infections with severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) show characteristic patterns, most frequently ground glass opacities (GGO) and a combination of GGO and air space consolidations. In the consecutive autopsy series of SARS-CoV‑2 deaths from Hamburg, Germany, the most frequent cause of death was and still is COVID-19 pneumonia. Typical findings were frequently found in the PMCT in SARS-CoV-2-associated deaths, which were taken into account when classifying the death as COVID-19.
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spelling pubmed-78840632021-02-16 COVID-19 lungs in post-mortem computed tomography Kniep, I. Heinemann, A. Edler, C. Sperhake, J. P. Püschel, K. Ondruschka, B. Schröder, A. S. Rechtsmedizin (Berl) Case Reports Post-mortem computed tomography (PMCT) is a rapid and noninvasive diagnostic tool for important contributions to the identification of pulmonary findings in the deceased with pneumonia, including cases of coronavirus disease 2019 (COVID-19). Although computed tomography (CT) shows a high sensitivity for pneumonia in living persons, it is relatively unspecific for COVID-19 pneumonia clinically. Typical CT findings for viral pneumonia therefore require confirmation by PCR tests (polymerase chain reaction tests), even if lung infections with severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) show characteristic patterns, most frequently ground glass opacities (GGO) and a combination of GGO and air space consolidations. In the consecutive autopsy series of SARS-CoV‑2 deaths from Hamburg, Germany, the most frequent cause of death was and still is COVID-19 pneumonia. Typical findings were frequently found in the PMCT in SARS-CoV-2-associated deaths, which were taken into account when classifying the death as COVID-19. Springer Medizin 2021-02-15 2021 /pmc/articles/PMC7884063/ /pubmed/33612977 http://dx.doi.org/10.1007/s00194-021-00462-z Text en © Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Case Reports
Kniep, I.
Heinemann, A.
Edler, C.
Sperhake, J. P.
Püschel, K.
Ondruschka, B.
Schröder, A. S.
COVID-19 lungs in post-mortem computed tomography
title COVID-19 lungs in post-mortem computed tomography
title_full COVID-19 lungs in post-mortem computed tomography
title_fullStr COVID-19 lungs in post-mortem computed tomography
title_full_unstemmed COVID-19 lungs in post-mortem computed tomography
title_short COVID-19 lungs in post-mortem computed tomography
title_sort covid-19 lungs in post-mortem computed tomography
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7884063/
https://www.ncbi.nlm.nih.gov/pubmed/33612977
http://dx.doi.org/10.1007/s00194-021-00462-z
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